Begin your full day of visiting Rome's highlights with a morning pick up from select hotels.
Head for the Vatican Museums, where you'll skip the long entry lines and the crowds to follow your tour guide directly inside. Explore the 54 galleries, including the Museo Gregoriano Egiziano, the Museo Gregoriano Etrusco, the Museo Chiaramonti, and the Museo Pio-Clementino, among others.
Enter the Sistine Chapel to see Michelangelo's famous ceiling fresco and learn about the events that still take place there, such as the Papal conclave. Continue to St. Peter's Basilica to take in the sheer size and the Renaissance architecture.
Stop to visit a local restaurant for lunch before continuing to the afternoon portion of your tour.
Again, skip the line for the Colosseum and explore the massive amphitheater with your guide, learning about its history as a source of entertainment for ancient Roman citizens.
Discover the Capitol Hill, the actual site of the Mayor of Rome, and offering the most beautiful view on the Roman Forum.
Then, you'll have the opportunity to visit Palatine Hill, the place of foundation of Rome and the Roman Forum from the inside, where your tour concludes.