Wake up early for pickup from European-side hotel to the airport for your full-day tour. Take a shortflight to Denizli, then travel to Pamukkale by car. First tour the red springs in the village of Karahayit. Next, head to the Roman spa town of Hierapolis, where you hear stories about the ancient city from your guide as you stroll past a necropolis, theater, and ancient market.
Then, visit the Cleopatra Antique Pool, where you can choose to pay a fee to swim in the thermal waters. Take some time to explore independently before rejoining your guide and group at a local restaurant for lunch.
Walk around the village of Pamukkale for a bit before heading back to Denizli. Finally, fly back to Istanbul and enjoy a ride back to your hotel.